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Publications

2016

Modulating the Amyloidogenesis of α-Synuclein.

K Sivanesam, NH Andersen. Modulating the Amyloidogenesis of α-Synuclein. Current Neuropharmacology, 14, 2016, 226-237.

Peptide Inhibitors of the amyloidogenesis of IAPP: verification of the hairpin-binding geometry hypothesis

K Sivanesam, I Shu, KNL Huggins, M Tatarek-Nossol, A Kapurniotu, NH Andersen. Peptide Inhibitors of the amyloidogenesis of IAPP: verification of the hairpin-binding geometry hypothesis FEBS Letters, 255, 2016, 2575-2583.

Optimization of a β-sheet-cap for long loop closure

JM Anderson, AA Shcherbakov, BL Kier, J Kellock, I Shu, AL Byrne, LA Eidenschink, NH Andersen Optimization of a β-sheet-cap for long loop closure Biopolymers, 0, 2016, .

Nascent Hairpins in Proteins: Identifying Turn Loci and Quantitating Turn Contributions to Hairpin Stability

JM Anderson, B Jurban, KN Huggins, AA Shcherbakov, I Shu, BL Kier, NH Andersen Nascent Hairpins in Proteins: Identifying Turn Loci and Quantitating Turn Contributions to Hairpin Stability Biochemistry, 55, 2016, 5537–5553.

Aryl-Aryl interactions in designed peptide folds: Spectroscopic characteristics and placement issues for optimal structure stabilization.

JM Anderson, B Kier, B Jurban, A Byrne, I Shu, LA Eidenschink, AA Shcherbakov, M Hudson, RM Fesinmeyer, NH Andersen Aryl-Aryl interactions in designed peptide folds: Spectroscopic characteristics and placement issues for optimal structure stabilization. Biopolymers, 105, 2016, 337-356.

2015

Disulfide-Mediated beta-Strand Dimers: Hyperstable beta-Sheets Lacking Tertiary Interactions and Turns

BL Kier, JM Anderson, NH Andersen Disulfide-Mediated beta-Strand Dimers: Hyperstable beta-Sheets Lacking Tertiary Interactions and Turns Journal of the American Chemical Society, 137, 2015, 5363-5371.

Binding Interactions of Agents That Alter alpha-Synuclein Aggregation

K Sivanesam, A Byrne, M Bisaglia, L Bubacco, NH Andersen Binding Interactions of Agents That Alter alpha-Synuclein Aggregation RSC Advances, 5, 2015, 11577-11590.

2014

An Improved Capping Unit for Stabilizing the Ends of Associated beta-Strands

JM Anderson, BL Kier, AA Shcherbakov and NH Andersen An Improved Capping Unit for Stabilizing the Ends of Associated beta-Strands FEBS Letters, 255, 2014, 4749-4753.

Folding Dynamics and Pathways of the Trp-cage Miniproteins

A Byrne, V Williams, B Barua, SJ Hagen, BL Kier, NH Andersen Folding Dynamics and Pathways of the Trp-cage Miniproteins Biochemistry, 53, 2014, 6011-6021.

Captides: Rigid Junctions between Beta Sheets and Small Molecules

BL Kier, NH Andersen Captides: Rigid Junctions between Beta Sheets and Small Molecules Journal of Peptide Science, 20, 2014, 704-715.

Circular Permutation of a WW Domain: Folding Still Occurs after Excising the Turn of the Folding-Nucleating Hairpin

BL Kier, JM Anderson, NH Andersen Circular Permutation of a WW Domain: Folding Still Occurs after Excising the Turn of the Folding-Nucleating Hairpin Journal of the American Chemical Society, 136, 2014, 741-749.

2013

Circular Permutation of the Trp-cage: Fold Rescue upon Addition of a Hydrophobic Staple

A Byrne, BL Kier, DV Williams, M Scian, NH Andersen Circular Permutation of the Trp-cage: Fold Rescue upon Addition of a Hydrophobic Staple RSC Advances, 3, 2013, 19824-19829.

13C structuring shifts for the analysis of model beta-hairpins and beta-sheets in proteins: diagnostic shifts appear only at the cross-strand H-bonded residues

Connecting Loop Effects on Beta-Strand Association Rates

BL Kier, JM Anderson, NH Andersen Connecting Loop Effects on Beta-Strand Association Rates Proceedings of the 23rd American Peptide Symposium, 0, 2013, 144-145.

Mutational Effects on the Folding Dynamics of a Minimized Hairpin

M Scian, I Shu, KA Olsen, K Hassam, NH Andersen Mutational Effects on the Folding Dynamics of a Minimized Hairpin Biochemistry, 52, 2013, 2556-2564.

Fluorescence of Tryptophan in Designed Hairpin and Trp-Cage Miniproteins: Measurements of Fluorescence Yields and Calculations by Quantum Mechanical Molecular Dynamics Simulations

A. W. McMillan, BL Kier, I Shu, AL Byrne, NH Andersen, W. W. Parson Fluorescence of Tryptophan in Designed Hairpin and Trp-Cage Miniproteins: Measurements of Fluorescence Yields and Calculations by Quantum Mechanical Molecular Dynamics Simulations Journal of Physical Chemistry B, 117, 2013, 1790–1809.

2012

Crystal and NMR structures of a Trp-cage mini-protein benchmark for computational fold prediction

M Scian, JC Lin, I Le Trong, G.I. Makhatadze, R.E Stenkamp, NH Andersen Crystal and NMR structures of a Trp-cage mini-protein benchmark for computational fold prediction PNAS, 109, 2012, 12521-12525.

2011

Designed hairpin peptides interfere with amyloidogenesis pathways: fibril formation and cytotoxicity inhibition, interception of the preamyloid state.

KNL Huggins, M Bisaglia, L Bubacco, M Tatarek-Nossol, A Kapurniotu, NH Andersen Designed hairpin peptides interfere with amyloidogenesis pathways: fibril formation and cytotoxicity inhibition, interception of the preamyloid state. Biochemistry, 50, 2011, 8202-8212.

Concerning the Optimal Salt Bridge for Trp-cage Stabilization

DV Williams, AL Byrne, JM Stewart, NH Andersen Concerning the Optimal Salt Bridge for Trp-cage Stabilization Biochemistry, 50, 2011, 1143-1152.

β-Sheet 13C Structuring Shifts Appear only at the H-bonded Sites of Hairpins

I Shu, JM Stewart, M Scian, BL Kier, NH Andersen β-Sheet 13C Structuring Shifts Appear only at the H-bonded Sites of Hairpins J. Am. Chem. Soc., 133, 2011, 1196-1199.

2010

Stabilizing Capping Motif for β Hairpins and Sheets

BL Kier, I Shu, L Eidenschink, NH Andersen Stabilizing Capping Motif for β Hairpins and Sheets Proc. Natl. Acad. Sci., 107, 2010, 10466-10471.

Designed Hairpins Modulate the Amyloidogenesis of α Synuclein: Inhibition and Diversion to Non-amyloid Aggregates

NH Andersen, KNL Huggins, M Bisaglia, L Bubacco Designed Hairpins Modulate the Amyloidogenesis of α Synuclein: Inhibition and Diversion to Non-amyloid Aggregates Proceedings of the 31st European Peptide Symposium, (M. Lebl, M. Meldal, K. J. Jensen, T. Hoeg-Jensen (Editors)), 0, 2010, 22-23.

2009

Development of Calcitonin Salmon Nasal Spray: Similarity of Peptide Formulated in Chlorobutanol Compared to Benzalkonium Chloride as Preservative

HR Costantino, H Culley, L Chen, D Morris, M Houston, S Roth, MJ Phoenix, C Foerder, JS Philo, T Arakawa, L Eidenschink, NH Andersen, G Brandt, SC Quay Development of Calcitonin Salmon Nasal Spray: Similarity of Peptide Formulated in Chlorobutanol Compared to Benzalkonium Chloride as Preservative Journal of Pharmaceutical Science, 98, 2009, 3691-3706.

Solution state structures of human pancreatic amylin and pramlintide

JR Cort, Z Liu, GM Lee, KNL Huggins,S Janes, K Prickett and NH Andersen Solution state structures of human pancreatic amylin and pramlintide Protein Engineering, Design and Selection , 22, 2009, 497-513.

Terminal Sidechain Packing of a Designed beta-Hairpin Influences Conformation and Stability

L Eidenschink, E Crabbe, NH Andersen Terminal Sidechain Packing of a Designed beta-Hairpin Influences Conformation and Stability Biopolymers, 91, 2009, 557-564.

Very Short Peptides With Stable Folds: Building on the Interrelationship of Trp/Trp, Trp/Cation, and Trp/Backbone-Amide Interaction Geometries

L Eidenschink, BL Kier, KNL Huggins, NH Andersen Very Short Peptides With Stable Folds: Building on the Interrelationship of Trp/Trp, Trp/Cation, and Trp/Backbone-Amide Interaction Geometries Proteins: Structure, Function, and Bioinformatics, 75, 2009, 308-322.

2008

Hyperstable miniproteins: additive effects of D- and L-Ala mutations

DV Williams, B Barua, NH Andersen Hyperstable miniproteins: additive effects of D- and L-Ala mutations Organic and Biomolecular Chemistry, 6, 2008, 4287-4289.

Probing the Lower Size Limit for Protein-Like Fold Stability: Ten-Residue Microproteins With Specific, Rigid Structures in Water

BL Kier, NH Andersen Probing the Lower Size Limit for Protein-Like Fold Stability: Ten-Residue Microproteins With Specific, Rigid Structures in Water Journal of the American Chemical Society, 130, 2008, 14675-14683.

Lysine and Arginine Residues Do Not Increase the Helicity of Alanine-rich Peptide Helices

JM Stewart, JC Lin, NH Andersen Lysine and Arginine Residues Do Not Increase the Helicity of Alanine-rich Peptide Helices Chemical Communications, 39, 2008, 4765-4767.

The Trp-cage: optimizing the stability of a globular miniprotein

B Barua, JC Lin, DV Williams, P Kummler, JW Neidigh, NH Andersen The Trp-cage: optimizing the stability of a globular miniprotein Protein Engineering Design & Selection, 21, 2008, 171-185.

2007

A Pre-existing Hydrophobic Collapse in the Unfolded State of an Ultrafast Folding Protein

KH Mok, LT Kuhn, M Goez, IJ Day, JC Lin, NH Andersen, PJ Hore A Pre-existing Hydrophobic Collapse in the Unfolded State of an Ultrafast Folding Protein Nature, 255, 2007, 106-109.

2006

Measuring Cooperativity in the Formation of a Three-stranded β-sheet (Double Hairpin)

Minimization and Optimization of Designed beta-Hairpin Folds

NH Andersen, KA Olsen, RM Fesinmeyer, X Tan, FM Hudson, L Eidenschink, SR Farazi Minimization and Optimization of Designed beta-Hairpin Folds Journal of the American Chemical Society, 128, 2006, 6101-6110.

2005

Chemical Shifts Provide Fold Populations and Register of β Hairpins and β Sheets

RM Fesinmeyer, FM Hudson, KA Olsen, GWN White, A Euser, NH Andersen Chemical Shifts Provide Fold Populations and Register of β Hairpins and β Sheets Journal of Biomolecular NMR, 33, 2005, 213-231.

A Slow, Tight-binding Inhibitor of the Zinc-Depedent Deacetylase LpxC in the Lipid A Biosynthetic Pathway

AL McClerren, SA Endsley, JL Bowman, NH Andersen, Z Guan, J Rudolph, CRH Raetz A Slow, Tight-binding Inhibitor of the Zinc-Depedent Deacetylase LpxC in the Lipid A Biosynthetic Pathway Biochemistry, 44, 2005, 16574-16583.

Hairpin Folding Rates Reflect Mutations Within and Remote from the Turn Region

KA Olsen, RM Fesinmeyer, JM Stewart, NH Andersen Hairpin Folding Rates Reflect Mutations Within and Remote from the Turn Region Proceedings of the National Academy of Sciences, USA, 102, 2005, 15483-15487.

Studies of helix fraying and solvation using 13C’ isotopomers

RM Fesinmeyer, ES Peterson, RB Dyer, NH Andersen Studies of helix fraying and solvation using 13C’ isotopomers Protein Science, 14, 2005, 2324-2332.

Hairpin Folding Dynamics: The Cold-Denatured State Is Predisposed for Rapid Refolding

RB Dyer, SJ Maness, S Franzen, RM Fesinmeyer, KA Olsen, NH Andersen Hairpin Folding Dynamics: The Cold-Denatured State Is Predisposed for Rapid Refolding Biochemistry, 44, 2005, 10406-10415.

2004

The Helical Alanine Controversy: An (Ala)6 Insertion Dramatically Increases Helicity

JC Lin, B Barua, NH Andersen The Helical Alanine Controversy: An (Ala)6 Insertion Dramatically Increases Helicity Journal of the American Chemical Society, 126, 2004, 13679-13684.

Exenatide: NMR/CD evaluation of the medium dependence of conformation and aggregation state

FM Hudson, NH Andersen Exenatide: NMR/CD evaluation of the medium dependence of conformation and aggregation state Biopolymers (Peptide Science), 76, 2004, 298-308.

The Mechanism of Beta-Hairpin Formation

RB Dyer, SJ Maness, ES Peterson, S Franzen, RM Fesinmeyer, NH Andersen The Mechanism of Beta-Hairpin Formation Biochemistry, 43, 2004, 11560-11566.

Enhanced Hairpin Stability through Loop Design: The Case of the Protein G B1 Domain Hairpin

RM Fesinmeyer, FM Hudson, NH Andersen Enhanced Hairpin Stability through Loop Design: The Case of the Protein G B1 Domain Hairpin Journal of the American Chemical Society, 126, 2004, 7238-7243.

2003

A Low-barrier Hydrogen Bond Between Histidine of Secreted Phospholipase A2 and a Transition State Analog Inhibitor

MJ Poi, J Tomaszewski, C Yuan, CA Dunlap, NH Andersen, MH Gelb, MD Tsai A Low-barrier Hydrogen Bond Between Histidine of Secreted Phospholipase A2 and a Transition State Analog Inhibitor Journal of Molecular Biology, 255, 2003, 997-1009.

Possible Locally Driven Folding Pathways of TC5b, a 20-residue Protein

GV Nikifororvich, NH Andersen, RM Fesinmeyer, C Frieden Possible Locally Driven Folding Pathways of TC5b, a 20-residue Protein Proteins, 52, 2003, 292-302.

2002

19F NMR Studies of Tryptophan/Serum Albumin Binding

B Cao, SA Endsley, NH Andersen 19F NMR Studies of Tryptophan/Serum Albumin Binding Bioorganic and Medicinal Chemistry, 11, 2002, 69-75.

Peptide Conformational Changes Induced by Tryptophan-Thosphocholine Interactions in a Micelle

Potent, Novel in Vitro Inhibitors of the Pseudomonas aeruginosa Deacetylase LpxC

T Kline, NH Andersen, EA Harwood, J Bowman, A Malanda, SA Endsley, AL Erwin, M Doyle, S Fong, AL Harris, B Mendelsohn, K Mdluli, CRH Raetz, CK Stover, PR Witte, A Yabannavar, and S Zhu Potent, Novel in Vitro Inhibitors of the Pseudomonas aeruginosa Deacetylase LpxC Journal of Medicinal Chemistry, 45, 2002, 3112-3129.

Designing a 20-Residue Protein

JW Neidigh, RM Fesinmeyer, NH Andersen Designing a 20-Residue Protein Nature Structural Biology, 9, 2002, 425-430.

Activation of Erythropoietin Receptor through a Novel Extracellular Binding Site

T Naranda, RI Kaufman, J Li, K Wong, A Boge, D Hallen, KYC Fung, MW Duncan, NH Andersen, A Goldstein, L Olsson Activation of Erythropoietin Receptor through a Novel Extracellular Binding Site Endocrinology, 143, 2002, 2293-2302.

Medium-Dependence of the secondary structure of exendin-4 and glucagon-like-peptide-1

NH Andersen, Y Brodsky, JW Neidigh, and KS Prickett Medium-Dependence of the secondary structure of exendin-4 and glucagon-like-peptide-1 Bioorganic and Medicinal Chemistry, 10, 2002, 79-85.

2001

Protein Structure, Stability, and Folding. Methods in Molecular Biology. Volume 168 Edited by Kenneth P. Murphy. Book Review

Modulating the Amyloidogenesis of α-Synuclein

K Sivanesam, NH Andersen Modulating the Amyloidogenesis of α-Synuclein Current Neuropharmacology, 14, 2016, 226-237.

Designed Hairpins Modulate the Amyloidogenesis of α Synuclein: Inhibition and Diversion to Non-amyloid Aggregates

NH Andersen, KNL Huggins, M Bisaglia, L Bubacco Designed Hairpins Modulate the Amyloidogenesis of α Synuclein: Inhibition and Diversion to Non-amyloid Aggregates Proceedings of the 31st European Peptide Symposium, (M. Lebl, M. Meldal, K. J. Jensen, T. Hoeg-Jensen (Editors)), 0, 2010, 22-23.

Dynamics of the Primary Processes of Protein Folding: Helix Nucleation

JH Werner, RB Dyer, RM Fesinmeyer, NH Andersen Dynamics of the Primary Processes of Protein Folding: Helix Nucleation Journal of Physical Chemistry, B, 106, 2002, 487-494.

Determinants of Miniprotein Stability: Can Anything Replace a Buried H-bonded Trp Sidechain?

B Barua, NH Andersen Determinants of Miniprotein Stability: Can Anything Replace a Buried H-bonded Trp Sidechain? Letters in Peptide Science, 8, 2002, 221-226.

Exendin-4 and Glucagon-like-peptide-1: NMR Structural Comparisons in the Solution and Micelle-Associated States

JW Neidigh, RM Fesinmeyer, KS Prickett, and NH Andersen Exendin-4 and Glucagon-like-peptide-1: NMR Structural Comparisons in the Solution and Micelle-Associated States Biochemistry, 40, 2001, 13188-13200.

1999

Effect of Hexafluoroisopropanol on the Thermodynamics of Peptide Secondary Structure Formation

NH Andersen, RB Dyer, RM Fesinmeyer, F Gai, Z Liu, JW Neidigh, and H Tong Effect of Hexafluoroisopropanol on the Thermodynamics of Peptide Secondary Structure Formation Journal of the American Chemical Society, 121, 1999, 9879-9880.

1997

Empirical Parameterization of a Model for Predicting Peptide Helix/Coil Equilibrium Populations

Formation of a Molten-Globule-Like State of Myoglobin in Aqueous Hexafluoroisopropanol

JR Cort and NH Andersen Formation of a Molten-Globule-Like State of Myoglobin in Aqueous Hexafluoroisopropanol Biochemical and Biophysical Research Communications, 233, 1997, 687-691.

Extracting Information from the Temperature Gradients of Polypeptide NH Chemical Shifts: I. The Importance of Conformational Averaging

NH Andersen, JW Neidigh, SM Harris, GM Lee, Z Liu, and H Tong Extracting Information from the Temperature Gradients of Polypeptide NH Chemical Shifts: I. The Importance of Conformational Averaging Journal of the American Chemical Society, 119, 1997, 8547-8561.

1996

Efforts Toward Deriving the CD Spectrum of a 3-10 Helix in Aqueous Medium

NH Andersen, Z Liu, and KS Prickett Efforts Toward Deriving the CD Spectrum of a 3-10 Helix in Aqueous Medium FEBS Letters, 255, 1996, 140-146.

Synthesis and X-ray Crystal Structure of 1,4-Dihydro-2,6-dimethyl-4-(2'-isopropylphenyl)-3,5-pyridine-dicarboxylic acid dimethyl ester: A Nifedipine Analogue

RB Palmer and NH Andersen Synthesis and X-ray Crystal Structure of 1,4-Dihydro-2,6-dimethyl-4-(2'-isopropylphenyl)-3,5-pyridine-dicarboxylic acid dimethyl ester: A Nifedipine Analogue Bioorganic and Medicinal Chemistry Letters, 6, 1996, 2173-2176.

Cold Denaturation of Monomeric Peptide Helices

NH Andersen, JR Cort, Z Liu, S Sjoberg, and H Tong Cold Denaturation of Monomeric Peptide Helices Journal of the American Chemical Society, 118, 1996, 10309-10310.

Conformational Dynamics of 4-Aryl-1,4-dihydropyridine Calcium Channel Antagonists. 1. Quantitation of C4-C1' Bond Rotation Barriers

RB Palmer, TM Andro, NR Natale, and NH Andersen Conformational Dynamics of 4-Aryl-1,4-dihydropyridine Calcium Channel Antagonists. 1. Quantitation of C4-C1' Bond Rotation Barriers Tetrahedron, 52, 1996, 9665-9680.

Conformational Preferences and Dynamics of 4-Isoxazolyl-1,4-dihydropyridine Calcium Channel Antagonists as Determined by Variable Temperature NMR and NOE Experiments

RB Palmer, TM Andro, NR Natale, and NH Andersen Conformational Preferences and Dynamics of 4-Isoxazolyl-1,4-dihydropyridine Calcium Channel Antagonists as Determined by Variable Temperature NMR and NOE Experiments Magnetic Resonance in Chemistry, 34, 1996, 495-504.

1995

Structural and Dynamic Properties of a b-Hairpin-Forming Linear Peptide. I. Modeling Using Ensemble- Averaged Constraints

KL Constantine, L Mueller, NH Andersen, H Tong, CF Wandler, MS Friedrichs, and RE Bruccoleri Structural and Dynamic Properties of a b-Hairpin-Forming Linear Peptide. I. Modeling Using Ensemble- Averaged Constraints Journal of the American Chemical Society, 117, 1995, 10841-10854.

Aryl-Dihydropyridine Rotational Barriers and Rotameric Preferences in Dihydropyridine Calcium Channel Antagonists

RB Palmer and NH Andersen Aryl-Dihydropyridine Rotational Barriers and Rotameric Preferences in Dihydropyridine Calcium Channel Antagonists Trends in Organic Chemistry, 5, 1995, 171-187.

The Endothelin C-Terminal Signal Fragment: Determinants of the Conformational Equilibrium in situ and Detached

NH Andersen, C Chen, and GM Lee The Endothelin C-Terminal Signal Fragment: Determinants of the Conformational Equilibrium in situ and Detached Protein and Peptide Letters, 1, 1995, 215-222.

The Receptor Binding Affinity of Monocyclic [Ala3, Xaa11]-Endothelin-1 Analogs Correlates with Inducible Helix Length

NH Andersen, SM Harris, VG Lee, ECK Liu, S Moreland, and JT Hunt The Receptor Binding Affinity of Monocyclic [Ala3, Xaa11]-Endothelin-1 Analogs Correlates with Inducible Helix Length Bioorganic and Medicinal Chemistry, 3, 1995, 113-124.

1994

b-Structure in Human Amylin and Two Designer b-Peptides: CD and NMR Spectroscopic Comparisons Suggest Soluble b-Oligomers and the Absence of Significant Populations of b-Strand Dimers

JR Cort, Z Liu, GM Lee, SM Harris, KS Prickett, LSL Gaeta, and NH Andersen b-Structure in Human Amylin and Two Designer b-Peptides: CD and NMR Spectroscopic Comparisons Suggest Soluble b-Oligomers and the Absence of Significant Populations of b-Strand Dimers Biochemical and Biophysical Research Communications, 204, 1994, 1088-1095.

Does the solid-state structure of endothelin-1 provide insights concerning the solution-state conformational equilibrium?

GM Lee, C Chen, TM Marschner, and NH Andersen Does the solid-state structure of endothelin-1 provide insights concerning the solution-state conformational equilibrium? FEBS Letters, 255, 1994, 140-146.

CD Studies of a Peptide Mimetic of L-Type Calcium Channels

NH Andersen and RB Palmer CD Studies of a Peptide Mimetic of L-Type Calcium Channels Bioorganic and Medicinal Chemistry Letters, 4, 1994, 817-822.

1993

A Comparison of BKCALC-Adjusted Constraints and Those from Program DISCON using Simulated Data for a B-DNA Structure

X Lai, B Reid, and NH Andersen A Comparison of BKCALC-Adjusted Constraints and Those from Program DISCON using Simulated Data for a B-DNA Structure Journal of Magnetic Resonance, Series B, 101, 1993, 288-293.

The DISCON Algorithm, an Accurate and Robust Alternative to an Eigenvalue Solution for Extracting Experimental Distances from NOESY Data

X Lai, C Chen, and NH Andersen The DISCON Algorithm, an Accurate and Robust Alternative to an Eigenvalue Solution for Extracting Experimental Distances from NOESY Data Journal of Magnetic Resonance, Series B, 101, 1993, 271-287.

Dactylocyclines: Novel Tetracycline Glycosides Active Against Tetracycline-resistant Bacteria

AA Tymiak, C Aklonis, MS Bolger, AD Kahle, DR Kirsch, J O'Sullivan, MA Porubcan, P Principe, WH Trejo. HA Ax, JS Wells, NH Andersen, P Devasthale, H Telikepalli, DV Velde, J-Y Zou and LA Mitsche Dactylocyclines: Novel Tetracycline Glycosides Active Against Tetracycline-resistant Bacteria Journal of Organic Chemistry, 58, 1993, 535-537.

Hevein: The NMR Assignment and an Assessment of Solution-state Folding for the Agglutinin-Toxin Motif

NH Andersen, B Cao, A Rodriguez, and B Arreguin Hevein: The NMR Assignment and an Assessment of Solution-state Folding for the Agglutinin-Toxin Motif Biochemistry, 32, 1993, 1407-1422.

1992

Peptide/Protein Structure Analysis using the Chemical Shift Index Method: Upfield a-CH Values Reveal Dynamic Helices and aL Sites

NH Andersen, B Cao, and C Chen Peptide/Protein Structure Analysis using the Chemical Shift Index Method: Upfield a-CH Values Reveal Dynamic Helices and aL Sites Biochemical and Biophysical Research Communications, 184, 1992, 1008-1014.

Dactylocyclines, Novel Tetracycline Derivatives Produced by a Dactylosporangium sp. II. Structure Elucidation

AA Tymiak, HA Ax, MS Bolger, AD Kahle, MA Porubcan, and NH Andersen Dactylocyclines, Novel Tetracycline Derivatives Produced by a Dactylosporangium sp. II. Structure Elucidation Journal of Antibiotics, 45, 1992, 1899-1906.

Solution Conformation of a Cyclic Pentapeptide Endothelin Antagonist: Comparison of Structures Obtained from Constrained Dynamics and Conformational Search

SR Krystek Jr., DA Bassolino, RE Bruccoleri, JT Hunt, MA Porubcan, CF Wandler and NH Andersen Solution Conformation of a Cyclic Pentapeptide Endothelin Antagonist: Comparison of Structures Obtained from Constrained Dynamics and Conformational Search FEBS Letters, 255, 1992, 255-261.

A Preparation of Imidazolyl Acids Tethered to Agarose Gels and Assessment of the Degree of Coupling for Affinity Chromatography

J Rhee and NH Andersen A Preparation of Imidazolyl Acids Tethered to Agarose Gels and Assessment of the Degree of Coupling for Affinity Chromatography Bulletin of the Korean Chemical Society, 13, 1992, 208-210.

An Approach to Isolation of Thromboxane Synthase by Ligand Tethered Affinity Techniques

NH Andersen and J Rhee An Approach to Isolation of Thromboxane Synthase by Ligand Tethered Affinity Techniques Bulletin of the Korean Chemical Society, 13, 1992, 119-122.

Conformational Isomerism of Endothelin in Acidic Aqueous Media: A Quantitative NOESY Analysis

NH Andersen, C Chen, TM Marschner, SR Krystek, and D Bassolino Conformational Isomerism of Endothelin in Acidic Aqueous Media: A Quantitative NOESY Analysis Biochemistry, 31, 1992, 1280-1295.

1991

Quantitative NOESY-Based Conformational Analysis of Endothelin-1 in Aqueous Media

NH Andersen, C Chen, TM Marschner, SR Krystek, D Bassolino, and J Novotny Quantitative NOESY-Based Conformational Analysis of Endothelin-1 in Aqueous Media Journal of Cellular Biochemistry, 15, 1991, 83.

A Conformation-Preference/Potency Correlation for GnRH analogs: NMR Evidence

NH Andersen and PK Hammen A Conformation-Preference/Potency Correlation for GnRH analogs: NMR Evidence Bioorganic and Medicinal Chemistry Letters, 1, 1991, 263-266.

Conformation of Endothelin in Aqueous Glycol Determined by 1H-NMR and molecular Dynamics Simulations

SR Krystek Jr., DA Bassolino, J Novotny, C Chen, TM Marschner and NH Andersen Conformation of Endothelin in Aqueous Glycol Determined by 1H-NMR and molecular Dynamics Simulations FEBS Letters, 255, 1991, 212-218.

Active Conformation of 1,4-Dihydropyridine Calcium Entry Blockers: Effect of Size of 2-Aryl Substituent on Aryl Rotamer Preference

G Rovnyak, NH Andersen, J Gougoutas, A Hedberg, SD Kimball, M Malley, S Moreland, M Porubcan and A Pudzianowski Active Conformation of 1,4-Dihydropyridine Calcium Entry Blockers: Effect of Size of 2-Aryl Substituent on Aryl Rotamer Preference Journal of Medicinal Chemistry, 34, 1991, 2521-2524.

1990

Computer-Aided Conformational Analysis Based on NOESY Signal Intensities

NH Andersen, X Lai, PK Hammen, and TM Marschner Computer-Aided Conformational Analysis Based on NOESY Signal Intensities NMR Applications in Biopolymers, 0, 1990, 95-134.

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