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Kelly Huggins

Graduate Student 2004-2010
khuggins@u.washington.edu

Post-doctoral Fellow, Stanford University

Ph.D. Chemistry, 2010
University of Washington, Seattle
Thesis: Designed Hairpin Peptides: Protein Folding Models and Inhibitors of Amyloid Fibril Formation
B.A. Biochemistry, 2004
Mount Holyoke College, South Hadley, MA

Publications

K Sivanesam, I Shu, KNL Huggins, M Tatarek-Nossol, A Kapurniotu, NH Andersen. Peptide Inhibitors of the amyloidogenesis of IAPP: verification of the hairpin-binding geometry hypothesis FEBS Letters 255 2016 2575-2583.

KNL Huggins, M Bisaglia, L Bubacco, M Tatarek-Nossol, A Kapurniotu, NH Andersen Designed hairpin peptides interfere with amyloidogenesis pathways: fibril formation and cytotoxicity inhibition, interception of the preamyloid state. Biochemistry 50 2011 8202-8212.

NH Andersen, KNL Huggins, M Bisaglia, L Bubacco Designed Hairpins Modulate the Amyloidogenesis of α Synuclein: Inhibition and Diversion to Non-amyloid Aggregates Proceedings of the 31st European Peptide Symposium, (M. Lebl, M. Meldal, K. J. Jensen, T. Hoeg-Jensen (Editors)) 0 2010 22-23.

JR Cort, Z Liu, GM Lee, KNL Huggins,S Janes, K Prickett and NH Andersen Solution state structures of human pancreatic amylin and pramlintide Protein Engineering, Design and Selection 22 2009 497-513.

L Eidenschink, BL Kier, KNL Huggins, NH Andersen Very Short Peptides With Stable Folds: Building on the Interrelationship of Trp/Trp, Trp/Cation, and Trp/Backbone-Amide Interaction Geometries Proteins: Structure, Function, and Bioinformatics 75 2009 308-322.

NH Andersen, KNL Huggins, M Bisaglia, L Bubacco Designed Hairpins Modulate the Amyloidogenesis of α Synuclein: Inhibition and Diversion to Non-amyloid Aggregates Proceedings of the 31st European Peptide Symposium, (M. Lebl, M. Meldal, K. J. Jensen, T. Hoeg-Jensen (Editors)) 0 2010 22-23.